KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RECQL4
All Species:
10
Human Site:
S325
Identified Species:
27.5
UniProt:
O94761
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94761
NP_004251.2
1208
133077
S325
R
Y
H
G
L
S
P
S
S
Q
A
R
A
G
K
Chimpanzee
Pan troglodytes
XP_520023
1208
133141
S325
R
Y
H
G
L
S
P
S
S
Q
A
R
A
G
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_539222
1209
131690
N318
Q
G
N
Y
V
R
L
N
L
K
Q
K
R
Y
V
Cat
Felis silvestris
Mouse
Mus musculus
Q75NR7
1216
135105
S317
V
P
Q
P
C
N
S
S
N
Q
A
R
T
E
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9I920
1142
126164
P316
E
T
A
P
E
A
P
P
P
P
Q
W
Q
P
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001920631
1380
154059
V452
Q
E
N
L
L
G
E
V
D
E
E
E
A
R
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393782
1284
145763
K359
K
T
N
D
L
S
S
K
S
I
I
K
P
R
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001187631
1990
223246
S764
K
R
L
N
I
S
P
S
A
P
P
S
K
R
R
Poplar Tree
Populus trichocarpa
XP_002315627
901
101082
S178
K
K
K
S
S
Y
A
S
S
S
R
G
F
Y
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
N.A.
57.8
N.A.
65.9
N.A.
N.A.
N.A.
21.1
N.A.
41.2
N.A.
N.A.
33.2
N.A.
27
Protein Similarity:
100
99.2
N.A.
66.7
N.A.
75
N.A.
N.A.
N.A.
35.4
N.A.
56.5
N.A.
N.A.
51.3
N.A.
39.3
P-Site Identity:
100
100
N.A.
0
N.A.
33.3
N.A.
N.A.
N.A.
6.6
N.A.
13.3
N.A.
N.A.
20
N.A.
20
P-Site Similarity:
100
100
N.A.
40
N.A.
46.6
N.A.
N.A.
N.A.
13.3
N.A.
33.3
N.A.
N.A.
40
N.A.
46.6
Percent
Protein Identity:
25
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
42
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
0
0
12
12
0
12
0
34
0
34
0
12
% A
% Cys:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
12
0
0
0
0
12
0
0
0
0
0
0
% D
% Glu:
12
12
0
0
12
0
12
0
0
12
12
12
0
12
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% F
% Gly:
0
12
0
23
0
12
0
0
0
0
0
12
0
23
12
% G
% His:
0
0
23
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
12
0
0
0
0
12
12
0
0
0
0
% I
% Lys:
34
12
12
0
0
0
0
12
0
12
0
23
12
0
34
% K
% Leu:
0
0
12
12
45
0
12
0
12
0
0
0
0
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
34
12
0
12
0
12
12
0
0
0
0
0
0
% N
% Pro:
0
12
0
23
0
0
45
12
12
23
12
0
12
12
0
% P
% Gln:
23
0
12
0
0
0
0
0
0
34
23
0
12
0
0
% Q
% Arg:
23
12
0
0
0
12
0
0
0
0
12
34
12
34
23
% R
% Ser:
0
0
0
12
12
45
23
56
45
12
0
12
0
0
0
% S
% Thr:
0
23
0
0
0
0
0
0
0
0
0
0
12
0
0
% T
% Val:
12
0
0
0
12
0
0
12
0
0
0
0
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% W
% Tyr:
0
23
0
12
0
12
0
0
0
0
0
0
0
23
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _